AJCN 19th International Congress of Nutrition
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by IZAK, G.
Right arrow Articles by GROSSOWICZ, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by IZAK, G.
Right arrow Articles by GROSSOWICZ, N.
Agricola
Right arrow Articles by IZAK, G.
Right arrow Articles by GROSSOWICZ, N.

American Journal of Clinical Nutrition, Vol 9, 473-477, Copyright © 1961 by The American Society for Clinical Nutrition, Inc.

Folic Acid Metabolites in Whole Blood and Serum in Anemia of Pregnancy

G. IZAK M.D.1, M. RACHMILEWITZ M.D.1, A. SADOVSKY M.D.1, B. BERCOVICI M.D.1, J. ARONOVITCH M.SC.1, and N. GROSSOWICZ PH.D.1

1 From the Departments of Medicine B, Obstetrics and Gynecology, Hadassah University Hospital, and the Department of Bacteriology, Hebrew University-Hadassah Medical School, Jerusalem, Israel

Folic acid determinations were carried out on whole blood and serum by means of three microbiologic assays. The total folic acid (conjugated and free pteroylglutamic acid and folinic acid) was determined by L. casei, free pteroylglutamic acid and folinic acid were determined by the use of Strep. fecalis, and P. cerevisiae was employed for the determination of folinic acid (citrovorum factor).

In sixty-four pregnant women with anemia, folic acid as well as serum iron and serum vitamin B12 levels were determined. In thirty-five of them, significantly low folic acid values were found in whole blood and serum when compared with values in normal subjects. Low folic acid values were frequently associated with low serum vitamin B12 and low serum iron concentration. The mechanism of the development of folic acid deficiency in pregnancy is discussed.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1961 by The American Society for Nutrition