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American Journal of Clinical Nutrition, Vol 8, 841-845, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

Riboflavin in Red Blood Cells in Relation to Dietary Intake of Children

VIRGINIA A. BEAL M.P.H.1 and JOHN J. VAN BUSKIRK B.S.1

1 From the Child Research Council, University of Colorado School of Medicine, Denver, Colorado

As part of a study of the growth and development of children, determinations of riboflavin in red blood cells and in the diet were done at stated intervals for several years on the same children. This paper presents the quartile values and the minimum and maximum levels of riboflavin in red blood cells and of the dietary intake of riboflavin per kg. of body weight. A correlation coefficient of +0.47 was found in 282 paired determinations on thirty-two boys and a coefficient of +0.46 in 334 paired determinations on thirty-six girls, ranging from one month to eighteen years of age. Infants tend to have higher levels of riboflavin in both dietary intake and red blood cells while children over ten years of age tend to have lower levels. Within each age group correlations indicate relatively little relationship between the dietary intake of riboflavin and the amount of that substance found in the red blood cells.




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S. Hustad, M. C. McKinley, H. McNulty, J. Schneede, J.J. Strain, J. M. Scott, and P. M. Ueland
Riboflavin, Flavin Mononucleotide, and Flavin Adenine Dinucleotide in Human Plasma and Erythrocytes at Baseline and after Low-Dose Riboflavin Supplementation
Clin. Chem., September 1, 2002; 48(9): 1571 - 1577.
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