AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by ESTREN, S.
Right arrow Articles by WASSERMAN, L. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by ESTREN, S.
Right arrow Articles by WASSERMAN, L. R.
Agricola
Right arrow Articles by ESTREN, S.
Right arrow Articles by WASSERMAN, L. R.

American Journal of Clinical Nutrition, Vol 8, 259-264, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

The Disappearance of Intravenously Administered Vitamin B12

Studies in Normal Subjects and in Patients with Pernicious Anemia

SOLOMON ESTREN M.D.1, EUGENE A. BRODY M.D.1, and LOUIS R. WASSERMAN M.D.1

1 From the Department of Hematology, The Mount Sinai Hospital, New York, New York

The fate of radioactive vitamin B12 following its intravenous injection was determined in normal subjects and in patients with chronic myelocytic leukemia and pernicious anemia.

The resulting plasma disappearance curves were abnormal patients with chronic myelocytic leukemia and pernicious anemia.

The abnormally slow plasma clearance of vitamin B12 found in pernicious anemia persisted even in patients in complete hematologic and clinical remission.

The concept of a circulating "serum B12-transferase" is suggested to explain these findings.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1960 by The American Society for Nutrition