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American Journal of Clinical Nutrition, Vol 8, 179-186, Copyright © 1960 by The American Society for Clinical Nutrition, Inc.

Hematologic Aspects of Sprue

FRANK H. GARDNER M.D.1

1 From the Richard C. Curtis Hematology Laboratory, Peter Bent Brigham Hospital, Boston, Massachusetts

Knowledge of the duration of malabsorption is helpful in comparing the hematologic defects seen in various types and phases of the sprue syndromes. Adequate therapies are available to correct the anemias observed in these disorders. A summary listing of the malutilization of the accepted hematinics is presented in Table II. The use of microbiologic assay and labeled nutrients has allowed a better understanding of erythropoiesis. Evidence is accumulating to imply that the factors initiating anemia are not nutritional depletion of hematinics per se but rather involvement of enzymes or constitutional defects.






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