| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
American Journal of Clinical Nutrition, Vol 66, 950-958, Copyright © 1997 by The American Society for Clinical Nutrition, Inc
ORIGINAL RESEARCH COMMUNICATIONS |
S Vogel, JH Contois, KL Tucker, PW Wilson, EJ Schaefer and CJ Lammi-Keefe
Department of Nutritional Sciences, University of Connecticut, Storrs 06269-4017, USA.
Data on plasma concentrations of tocopherols and the major carotenoids in adults aged > or = 65 y, particularly in those > 80 y, are sparse. In the current study retinol, tocopherol (alpha- and gamma- tocopherols), and carotenoid (lutein/zeaxanthin, cryptoxanthins, lycopene, and alpha- and beta-carotene) concentrations were determined in 638 subjects, 230 men (aged 75 +/- 5 y) and 408 women (76 +/- 6 y), of the Framingham Heart Study. All subjects were free of clinical evidence of cardiovascular disease and cancer. Percentile ranges were comparable with those established in younger cohorts. Moreover, women had significantly higher plasma alpha-tocopherol and plasma and lipoprotein concentrations of beta-cryptoxanthin and alpha- and beta- carotene than did men. Lycopene concentrations were inversely correlated with age and lowest among subjects > or = 80 y. Total intakes (diet+supplements) of vitamin C and vitamin E, but not dietary intakes alone, were positively associated with plasma alpha-tocopherol and inversely associated with gamma-tocopherol concentrations. In multivariate analyses, plasma cholesterol and triacylglycerol concentrations and total intake of vitamins E and C predicted 64% and 55% of the plasma alpha-tocopherol concentrations in men and women, respectively. Important predictors for the majority of carotenoids included plasma cholesterol concentration, body mass index (negative effect), and smoking status (negative effect); for lycopene concentration they included cholesterol concentration and age (negative effect). In summary, percentile ranges and lipoprotein distributions were comparable with those established in younger cohorts, suggesting that overall antioxidant status is not altered in people between the ages of 67 and 96 y.
This article has been cited by other articles:
|
|
 |
|
  P. Palozza, R. Sestito, N. Picci, P. Lanza, G. Monego, and F. O. Ranelletti The sensitivity to {beta}-carotene growth-inhibitory and proapoptotic effects is regulated by caveolin-1 expression in human colon and prostate cancer cells Carcinogenesis, November 1, 2008; 29(11): 2153 - 2161. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Talegawkar, E. J. Johnson, T. Carithers, H. A. Taylor Jr., M. L. Bogle, and K. L. Tucker Total {alpha}-Tocopherol Intakes Are Associated with Serum {alpha}-Tocopherol Concentrations in African American Adults J. Nutr., October 1, 2007; 137(10): 2297 - 2303. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. G Traber How much vitamin E? ... Just enough! Am. J. Clinical Nutrition, November 1, 2006; 84(5): 959 - 960. [Full Text] [PDF]
|
|
|
|
|
|
I. Aeberli, L. Molinari, G. Spinas, R. Lehmann, D. l'Allemand, and M. B Zimmermann Dietary intakes of fat and antioxidant vitamins are predictors of subclinical inflammation in overweight Swiss children. Am. J. Clinical Nutrition, October 1, 2006; 84(4): 748 - 755. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A. M. Zornoff, L. S. Matsubara, B. B. Matsubara, M. P. Okoshi, K. Okoshi, M. Dal Pai-Silva, R. F. Carvalho, A. C. Cicogna, C. R. Padovani, E. L. Novelli, et al. Beta-Carotene Supplementation Attenuates Cardiac Remodeling Induced by One-Month Tobacco-Smoke Exposure in Rats Toxicol. Sci., March 1, 2006; 90(1): 259 - 266. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. M. Clark, K. L. Herron, D. Waters, and M. L. Fernandez Hypo- and Hyperresponse to Egg Cholesterol Predicts Plasma Lutein and {beta}-Carotene Concentrations in Men and Women J. Nutr., March 1, 2006; 136(3): 601 - 607. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. R. Switzer, J. R. Atwood, A. H. Stark, J. W. Hatch, R. Travis, F. Ullrich, E. R. Lyden, X. Wu, Y. Chiu, and J. L. Smith Plasma Carotenoid and Vitamins A and E Concentrations in Older African American Women after Wheat Bran Supplementation: Effects of Age, Body Mass and Smoking History J. Am. Coll. Nutr., June 1, 2005; 24(3): 217 - 226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. D Sesso, J. E Buring, E. P Norkus, and J M. Gaziano Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men Am. J. Clinical Nutrition, May 1, 2005; 81(5): 990 - 997. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ortega, P. Castilla, D. Gomez-Coronado, C. Garces, M. Benavente, F. Rodriguez-Artalejo, M. de Oya, and M. A Lasuncion Influence of apolipoprotein E genotype on fat-soluble plasma antioxidants in Spanish children Am. J. Clinical Nutrition, March 1, 2005; 81(3): 624 - 632. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Ganji and M. R. Kafai Population Determinants of Serum Lycopene Concentrations in the United States: Data from the Third National Health and Nutrition Examination Survey, 1988-1994 J. Nutr., March 1, 2005; 135(3): 567 - 572. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Jordan, A. J. De Roos, J. B. Renner, G. Luta, A. Cohen, N. Craft, C. G. Helmick, M. C. Hochberg, and L. Arab A Case-Control Study of Serum Tocopherol Levels and the Alpha- to Gamma-Tocopherol Ratio in Radiographic Knee Osteoarthritis: The Johnston County Osteoarthritis Project Am. J. Epidemiol., May 15, 2004; 159(10): 968 - 977. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. C. Tangney, J. L. Bienias, D. A. Evans, and M. C. Morris Reasonable Estimates of Serum Vitamin E, Vitamin C, and {beta}-Cryptoxanthin Are Obtained with a Food Frequency Questionnaire in Older Black and White Adults J. Nutr., April 1, 2004; 134(4): 927 - 934. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. D Sesso, J. E Buring, E. P Norkus, and J M. Gaziano Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women Am. J. Clinical Nutrition, January 1, 2004; 79(1): 47 - 53. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Blakely, A. Herbert, M. Collins, M. Jenkins, G. Mitchell, E. Grundel, K. R. O'Neill, and F. Khachik Lutein Interacts with Ascorbic Acid More Frequently than with {alpha}-Tocopherol to Alter Biomarkers of Oxidative Stress in Female Zucker Obese Rats J. Nutr., September 1, 2003; 133(9): 2838 - 2844. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. S Ford, C. Gillespie, C. Ballew, A. Sowell, and D. M Mannino Serum carotenoid concentrations in US children and adolescents Am. J. Clinical Nutrition, October 1, 2002; 76(4): 818 - 827. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Jang, J. H. Lee, O. Y. Kim, H. Y. Park, and S. Y. Lee Consumption of Whole Grain and Legume Powder Reduces Insulin Demand, Lipid Peroxidation, and Plasma Homocysteine Concentrations in Patients With Coronary Artery Disease: Randomized Controlled Clinical Trial Arterioscler. Thromb. Vasc. Biol., December 1, 2001; 21(12): 2065 - 2071. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. G Rowley, Q. Su, M. Cincotta, M. Skinner, K. Skinner, B. Pindan, G. A White, and K. O'Dea Improvements in circulating cholesterol, antioxidants, and homocysteine after dietary intervention in an Australian Aboriginal community Am. J. Clinical Nutrition, October 1, 2001; 74(4): 442 - 448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. El-Sohemy, A. Baylin, A. Ascherio, E. Kabagambe, D. Spiegelman, and H. Campos Population-based study of {alpha}- and {gamma}-tocopherol in plasma and adipose tissue as biomarkers of intake in Costa Rican adults Am. J. Clinical Nutrition, September 1, 2001; 74(3): 356 - 363. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Jang, J. H. Lee, E. Y. Cho, N. S. Chung, D. Topham, and B. Balderston Differences in body fat distribution and antioxidant status in Korean men with cardiovascular disease with or without diabetes Am. J. Clinical Nutrition, January 1, 2001; 73(1): 68 - 74. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Patrignani, M. R. Panara, S. Tacconelli, F. Seta, T. Bucciarelli, G. Ciabattoni, P. Alessandrini, A. Mezzetti, G. Santini, M. G. Sciulli, et al. Effects of Vitamin E Supplementation on F2-Isoprostane and Thromboxane Biosynthesis in Healthy Cigarette Smokers Circulation, August 1, 2000; 102(5): 539 - 545. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Watzl, A. Bub, M. Blockhaus, B. M. Herbert, P. M. Lührmann, M. Neuhäuser-Berthold, and G. Rechkemmer Prolonged Tomato Juice Consumption Has No Effect on Cell-Mediated Immunity of Well-Nourished Elderly Men and Women J. Nutr., July 1, 2000; 130(7): 1719 - 1723. [Abstract] [Full Text]
|
|
|
|
|
|
M. A. Hallikainen, E. S. Sarkkinen, and M. I. J. Uusitupa Plant Stanol Esters Affect Serum Cholesterol Concentrations of Hypercholesterolemic Men and Women in a Dose-dependent Manner J. Nutr., April 1, 2000; 130(4): 767 - 776. [Abstract] [Full Text]
|
|
|
|
|
|
S. A.R. Paiva and R. M. Russell {beta}-Carotene and Other Carotenoids as Antioxidants J. Am. Coll. Nutr., October 1, 1999; 18(5): 426 - 433. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. T. Mayne, B. Cartmel, F. Silva, C. S. Kim, B. G. Fallon, K. Briskin, T. Zheng, M. Baum, G. Shor-Posner, and W. J. Goodwin Jr. Plasma Lycopene Concentrations in Humans Are Determined by Lycopene Intake, Plasma Cholesterol Concentrations and Selected Demographic Factors J. Nutr., April 1, 1999; 129(4): 849 - 854. [Abstract] [Full Text]
|
|
|
|
|
|
K. L Tucker, H. Chen, S. Vogel, P. W. F. Wilson, E. J. Schaefer, and C. J. Lammi-Keefe Carotenoid Intakes, Assessed by Dietary Questionnaire, Are Associated with Plasma Carotenoid Concentrations in an Elderly Population J. Nutr., February 1, 1999; 129(2): 438 - 445. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Paiva, K.-J. Yeum, G. Cao, R. L. Prior, and R. M. Russell Postprandial Plasma Carotenoid Responses Following Consumption of Strawberries, Red Wine, Vitamin C or Spinach by Elderly Women J. Nutr., December 1, 1998; 128(12): 2391 - 2394. [Abstract] [Full Text]
|
|
|
|
|
|
K.-J. Yeum, S.-H. Ahn, S. A. Rupp de Paiva, Y. C. Lee-Kim, N. I. Krinsky, and R. M. Russell Correlation between Carotenoid Concentrations in Serum and Normal Breast Adipose Tissue of Women with Benign Breast Tumor or Breast Cancer J. Nutr., November 1, 1998; 128(11): 1920 - 1926. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
