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American Journal of Clinical Nutrition, Vol 35, 250-257, Copyright © 1982 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

A factor in food which impairs Na+-K+-ATPase in vitro

DM Harlan and GV Mann

Extracts of foods were examined to identify materials which inactivate Na+-K+-dependent ATPase. Active material which we call food factor was found in tea, cocoa, red wines, and in certain other dietary components. A unit of activity is defined and the material is compared with ouabain and an inhibitory flavone. The possible role of such a food factor in the regulation of sodium metabolism and in the causation of essential high blood pressure is discussed.




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Copyright © 1982 by The American Society for Nutrition