AJCN Cancer Health Disparities Conference
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rosholt, M. N.
Right arrow Articles by Hegarty, P. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rosholt, M. N.
Right arrow Articles by Hegarty, P. V.
Agricola
Right arrow Articles by Rosholt, M. N.
Right arrow Articles by Hegarty, P. V.

American Journal of Clinical Nutrition, Vol 34, 1680-1685, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Mineralization of different bones in streptozotocin-diabetic rats: study on the concentration of eight minerals

MN Rosholt and PV Hegarty

Streptozotocin-induced diabetes was studied in male and female rats weighing 188 and 145 g, respectively, at the start of the experiment. After 79 days in the diabetic condition the weights and lengths of different bones were less in the diabetic rats than in two nondiabetic control groups, i.e., ad libitum fed and a group restricted in food intake to achieve the same body weight as the diabetic rats. The concentrations of calcium, phosphorus, and sodium were similar in the diabetic and nondiabetic groups, whereas the concentrations of iron and zinc were higher in the diabetic rats. Results for the concentration of potassium, magnesium, and chromium showed a less uniform pattern between groups and between males and females. It is concluded that the length and weight of bones in diabetic rats are less than nondiabetic rats of the same body weight. This results in a lower total amount of calcium, phosphorus, sodium, potassium, magnesium, and chromium. This observation was similar in all three bones studied. Therefore, prolonged streptozotocin-induced diabetes does interfere with the normal pattern of bone mineralization.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by The American Society for Nutrition