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American Journal of Clinical Nutrition, Vol 34, 2088-2091, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Nonresponsiveness of serum high-density lipoprotein-cholesterol to high dose ascorbic acid administration in normal men

GE Johnson and SS Obenshain

In a prospective, single-blind, 12-wk study, serum lipids were measured serially in nine normal male volunteers before and during oral administration of megadose ascorbic acid (1 g vitamin C/day). Study results revealed no significant effect of vitamin therapy on serum cholesterol, high-density lipoprotein-cholesterol, triglycerides, or calculated low-density lipoprotein-cholesterol. Megadose ascorbic acid therapy is not effective in elevating serum high-density lipoprotein- cholesterol in normal adult men.


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A. D. Mooradian, M. J. Haas, and N. C. W. Wong
The Effect of Select Nutrients on Serum High-Density Lipoprotein Cholesterol and Apolipoprotein A-I Levels
Endocr. Rev., February 1, 2006; 27(1): 2 - 16.
[Abstract] [Full Text] [PDF]


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Copyright © 1981 by The American Society for Nutrition