AJCN 19th International Congress of Nutrition
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Donaldson, M. L.
Right arrow Articles by Gubler, C. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Donaldson, M. L.
Right arrow Articles by Gubler, C. J.
Agricola
Right arrow Articles by Donaldson, M. L.
Right arrow Articles by Gubler, C. J.

American Journal of Clinical Nutrition, Vol 31, 859-864, Copyright © 1978 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Biochemical effects of mercury poisoning in rats

ML Donaldson and CJ Gubler

Acute HgCl2 poisoning was shown to decrease significantly the pyruvate dehydrogenase (PyDH) and alpha-ketoglutanic dehydrogenese (alphaKgDH) activity in the kidney and liver but not in the brain. Rats receiving 77% of the 2 hr 50% lethal dose showed 57% of normal renal PyDH activity and 69% of normal renal alphaKgDH activity. Chronic Hg Cl2 poisoning resulted in an unexpected increase in PyDH and alphaKgDH activity in the kidneys where mercury was most concentrated. In acute methyl mercury injection, no significant effect on PyDH or alpha KgDH activities was observed after 2 days. Less mercury was accumulated in the tissues with methyl mercury poisoning than in the other treatments.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by The American Society for Nutrition