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American Journal of Clinical Nutrition, Vol 31, 451-456, Copyright © 1978 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Are proteinase inhibitors a factor for the derangement of homoeostasis in protein-energy malnutrition?

FP Schelp, P Migasena, P Pongpaew and WH Schreurs

In protein-energy malnutrition essential amino acids for the synthesis of proteins are derived from the mobilization of endogenous proteins in order to maintain homoeostasis. Data are presented to support the hypothesis that proteinase inhibitors, which increase rapidly at the onset of infection, interrupt this catabolic effect which is the normal adaptive response to protein-energy malnutrition.




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Copyright © 1978 by The American Society for Nutrition