AJCN North Carolina Research Campus
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Purchase Article
Right arrow View Shopping Cart
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ingenbleek, Y.
Right arrow Articles by Beckers, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ingenbleek, Y.
Right arrow Articles by Beckers, C.
Agricola
Right arrow Articles by Ingenbleek, Y.
Right arrow Articles by Beckers, C.

American Journal of Clinical Nutrition, Vol 31, 408-415, Copyright © 1978 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Thyroid iodide clearance and radioiodide uptake in protein-calorie malnutrition

Y Ingenbleek and C Beckers

The thyroid function was evaluated in two comparable groups of 12 protein-calorie malnourished children respectively by oral and intravenous test using radioiodine 131I. Maximal radioiodide uptake (RAIUmax) peaked within 24 hr in the intravenously investigated children, but only after 48 hr in the orally investigated children. In both protein-calorie malnutrition groups, the mean RAIUmax was significantly decreased by comparison with the mean normal RAIUmax (P less than 0.01). In protein-calorie malnutrition children, the RAIU curve reached intermediate values ranging from subnormal to about nearly half the normal. Thyroid clearance was early depressed and in some cases, dropped to values as low as one tenth of the normal mean (P less than 0.001), reflecting a severe thyroid involution. There is a high correlation between the RAIUmax and thyroid clearance values (r = 0.95); the regression line is defined by the equation Y = 1.12X + 17.08. Both functional parameters of thyroid activity appear to be mainly lowered in relation to the duration of protein deficiency.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by The American Society for Nutrition