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American Journal of Clinical Nutrition, Vol 30, 367-370, Copyright © 1977 by The American Society for Clinical Nutrition, Inc


ORIGINAL RESEARCH COMMUNICATIONS

Defective local leukocyte mobilization in children with kwashiorkor

P Kulapongs, R Edelman, R Suskind and RE Olson

The Rebuck window technique was used to determine the functional integrity of the inflammatory response in nine children with kwashiorkor. The total numbers of leukocytes mobilized into skin abrasions were similar between kwashiorkor and control patients. However, children with kwashiorkor showed significantly delayed and decreased macrophage migration and increased polymorphonuclear leukocyte migration. These defects of leukocyte mobilization were corrected with nutritional repair.


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