AJCN 19th International Congress of Nutrition
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American Journal of Clinical Nutrition, Vol 30, 64-71, Copyright © 1977 by The American Society for Clinical Nutrition, Inc

ORIGINAL RESEARCH COMMUNICATIONS

Hyperoxaluria and calcium oxalate nephrolithiasis after jejunoileal bypass

JQ Stauffer

Patients with ileal disease, ileal resection, and jejunoileal bypass are at increased risk of forming calcium oxalate renal calculi because of enhanced absorption of dietary oxalate. Intraluminal solubility of oxalate is an important determinant for hyperabsorption and may be regulated by intraluminal concentration of calcium and fatty acids. Malabsorbed bile salts and fatty acids may alter intestinal permeability, leading to increased passive diffusion of oxalate. Management includes a diet low in oxalate and fat content, dietary calcium of 750 mg/day, and cholestyramine.


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J. A. Requarth, K. W. Burchard, T. A. Colacchio, T. A. Stukel, L. A. Mott, E. R. Greenberg, and R. E. Weismann
Long-term Morbidity Following Jejunoileal Bypass: The Continuing Potential Need for Surgical Reversal
Arch Surg, March 1, 1995; 130(3): 318 - 325.
[Abstract] [PDF]


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Copyright © 1977 by The American Society for Nutrition