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American Journal of Clinical Nutrition, Vol 27, 1221-1224, Copyright © 1974 by The American Society for Clinical Nutrition, Inc.

Vitamin B1 status in pregnancy

Sigfried Heller 1, Richard M. Salkeld 1, and Wilhelm F. Körner 1

1 From the University Obstetric Clinic, Tübingen, Germany and the Department of Vitamin and Nutrition Research, F. Hoffmann-La Roche & Co., Ltd., Basle, Switzerland

The vitamin B1 status of 599 pregnant women was investigated by means of the erythrocyte transketolase-activation test. No correlation between the vitamin B1 status and the course or outcome of pregnancy could be demonstrated. In contrast, 25-30% were found to be thiamin-depleted in respect of erythrocyte transketolase saturation in comparison with a group of over 300 male and female blood donors. This proportion remained constant throughout gestation. As a consequence, vitamin B1 supplementation is recommended to prevent subclinical metabolic disturbances of thiamin-dependent enzyme systems.






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Copyright © 1974 by The American Society for Nutrition