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American Journal of Clinical Nutrition, Vol 25, 1174-1178, Copyright © 1972 by The American Society for Clinical Nutrition, Inc.

Effects of dietary protein restriction on albumin synthesis, albumin catabolism, and the plasma aminogram

L. Kelman M.B., Ch.B., M.D.1, S. J. Saunders M.B., Ch.B., M.D., F.R.C.P.1, L. Frith B.Sc.1, S. Wicht B.Sc.1, and A. Corrigal B.Sc.1

1 From the Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa

Albumin synthesis, albumin catabolism, and the plasma aminogram were studied in eight patients on both normal and low protein diets.

The fractional and absolute synthesis rates of albumin were markedly reduced by protein restriction. Catabolic rates were reduced to a lesser degree.

Plasma alanine was increased by protein restriction. The other amino acids were unaffected.




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