AJCN 19th International Congress of Nutrition
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American Journal of Clinical Nutrition, Vol 19, 77-83, Copyright © 1966 by The American Society for Clinical Nutrition, Inc.

Total Body Water in Obesity

KARE GUNDERSEN M.D.1 and GRACE SHEN M.S.1

1 From the Department of Preventive Medicine, New England Medical Center Hospitals and Tufts University School of Medicine, Boston, Massachusetts

Determinations of total body water by the use of intravenously administered tritiated water in normal subjects and in subjects of varying degrees of obesity showed an inverse linear relationship between percentage total body water and percentage overweight. However, this relationship was less clearly seen in extreme obesity, when water retention appeared to be present in most cases, as evidenced by a gradual return of per cent total body water to a calculated curve after prolonged dieting; sodium and nitrogen balance studies also indicated that a large portion of the weight loss was due to diuresis. Sodium balance studies and repeated tritiated water determinations agreed well in estimating water loss.






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Copyright © 1966 by The American Society for Nutrition