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American Journal of Clinical Nutrition, Vol 12, 230-234, Copyright © 1963 by The American Society for Clinical Nutrition, Inc.

Chorionic Gonadotropin in the Treatment of Obese Women

LEELA S. CRAIG M.D.1, RUTH E. RAY M.D.1, SAMUEL H. WAXLERM M.D.1, and HELEN MADIGAN B.S.1

1 From the Department of Medicine and the Nutrition Clinic, University of California School of Medicine, San Francisco, California

No effect of chorionic gonadotropin therapy in producing weight loss was found in a study on a group of twenty obese clinic patients. The women were treated for a forty-day period with a 550 calorie diet and a daily injection of either chorionic gonadotropin or a placebo solution, administered by the double-blind technic. All but one subject lost weight, but the losses were small and not uniform, suggesting varied adherence to the diet. The basal metabolic rate was increased in four treated patients and two control subjects. These changes could not be correlated with weight loss, apparent adherence to diet or protein-bound iodine levels.




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[Abstract] [Full Text]


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