AJCN 19th International Congress of Nutrition
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American Journal of Clinical Nutrition, Vol 10, 525-530, Copyright © 1962 by The American Society for Clinical Nutrition, Inc.

Hepatocellular Lipoid Changes in Pantothenic Acid Deficiency

ZOLTON T. WIRTSCHAFTER M.D.1 and JOHN R. WALSH M.D.1

1 From The Research Laboratory, V. A. Hospital, and the University of Oregon Medical School, Portland, Oregon

Mature rats on a pantothenic acid-deficient diet showed hepatic changes characterized by progressive increase in lipid globules in the central, periportal and mid-zonal areas. Morphological studies employing oil red O technic clearly established the relationship of hepatocellular damage to the deprivation of pantothenic acid.






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Copyright © 1962 by The American Society for Nutrition