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American Journal of Clinical Nutrition, Vol 10, 332-336, Copyright © 1962 by The American Society for Clinical Nutrition, Inc.

Effect of the Mode of Feeding of Fats on Serum Cholesterol Levels and Plasma Fibrinolytic Activity of Monkeys

C. GOPALAN M.D., PH.D.1, S. G. SRIKANTIA B.SC., M.B.B.S.1, S. N. JAGANNATHAN M.SC.1, and K. S. RAMANATHAN 1

1 From the Nutrition Research Laboratories, Indian Council of Medical Research, Hyderabad, India

The effects of "continuous" and "intermittent" feeding of a high fat diet to two groups of monkeys have been compared. Although the food intake was nearly the same in both groups, body weight was higher in animals fed intermittently that in those fed continuously at the end of the experimental period. This difference, however, was not statistically significant.

Serum cholesterol concentration was significantly higher and plasma fibrinolytic activity significantly lower in the intermittently fed group than in the continuously fed group. The results indicate the importance of the mode of distribution of fat in the daily diet.






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