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American Journal of Clinical Nutrition, Vol 1, 417-423, Copyright © 1953 by The American Society for Clinical Nutrition, Inc.

VITAMIN B12 Excretion and DIABETIC RETINOPATHY

BERNARD BECKER M.D.1, CALVIN A. LANG A.B.1, and BACON F. CHOW PH.D.1

1 From the Department of Biochemistry, School of Hygiene and Public Health, The Johns Hopkins Univ. and The Wilmer Institute, The Johns Hopkins Hospital, Baltimore, Maryland

Following an intramuscular test dose of vitamin B12, diabetic subjects with retinopathy excrete significantly more of the vitamin than non-diabetics; while diabetics without retinopathy excrete considerably less than the non-diabetics.

Administration of testosterone to diabetics with retinopathy decreases the urinary excretion of a test dose of vitamin B12. Cortisone increases the test dose excretion of vitamin B12 in rats.






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Copyright © 1953 by The American Society for Nutrition